Immune Response to Simulated Postexposure Rabies Booster Vaccinations in Volunteers Who Received Preexposure Vaccinations

Immune responses of elk to initial and booster vaccinations with Brucella abortus strain RB51 or 19.

Previous studies have suggested that currently available brucellosis vaccines induce poor or no protection in elk (Cervus elaphus nelsoni). In this study, we characterized the immunologic responses of elk after initial or booster vaccination with Brucella abortus strains RB51 (SRB51) and 19 (S19). Elk were vaccinated with saline or 10(10) CFU of SRB51 or S19 (n=seven animals/treatment) and boos...

Postexposure rabies prophylaxis protocol for domestic animals and epidemiologic characteristics of rabies vaccination failures in Texas: 1995-1999.

OBJECTIVE To determine whether postexposure rabies prophylaxis (PEP) in domestic animals, as mandated by the state of Texas, has continued to be effective and to evaluate PEP and preexposure rabies vaccination failures from 1995 through 1999. DESIGN Retrospective study. ANIMALS 830 unvaccinated domestic animals (621 dogs, 78 horses, 71 cats, and 60 cattle) that received PEP and 4 animals (3...

Rabies vaccinations: are abbreviated intradermal schedules the future?

Rabies is a deadly disease, and current preexposure vaccination schedules are lengthy and expensive. We identified nine studies investigating abbreviated schedules. Although initial responses were lower, accelerated adequate immune responses were elicited after booster vaccinations. Lower-dose (and therefore cheaper) vaccination schedules may constitute a valid alternative to current vaccinatio...

Vaccinations of International Travelers

Creating artificial barriers to vaccinations.

Achieving optimum outcomes is difficult enough without creating artificial barriers. Certainly none of us would ever admit to putting up any barrier that would prevent our residents from gaining access to important medical care; however, that it exactly what we have been doing by requiring signed consents for influenza and pneumococcal vaccinations in long-term care facilities. This is a seriou...